A study by Ralf Bartenschlager has been published in the journal Nature Communications
The main aim of the project was to identify the morphological changes within a cell that are triggered by SARS-CoV‑2. The team was able to create 3D reconstructions of whole cells and their subcellular compartments. "We are providing critical insights into virus-induced structural changes in the studied human cells," says Ralf Bartenschlager, who worked on the project with other researchers EMBL Heidelberg.
The insights gained represent a valuable surplus for the entire research world. "This way we can support the global effort to study how SARS-CoV‑2 interacts with its host," says Yannick Schwab, who also contributed to the project. The team hopes that their collected information will help in the development of antiviral drugs.