1,3‑Diketon Based Ligands for Transition Metal Catalysis
Jonas Wunsch – Hector Fellow A. Stephen K. Hashmi
The development of catalysts to increase the chemical efficiency or to find completely new chemical reactions has found great interest. For this a wide variety of ligands are needed.
The doctoral is supervised by Hector Fellow A. Stephen K. Hashmi and aims at developing new ligands that are based on the formal double deprotonation of 1,3‑diketones and thereby enlarging the chemical space of known ligands. For this new synthetic methods have to be found and the obtained ligands have to be tested and characterised.
Catalytic Reactions enable many energy efficient chemical reactions. Also a small amount of a catalyst instead of a stoichiometric amount of an activation reagent can be used which strongly cuts waste production. Urgent problems like climate change and increasing resource shortage highlight the importance of developing new catalyst to mitigate these problems. The choice of the ligands at the active metal centre is essential for the catalytic properties. The most important influences of the ligands are steric and electronic parameters.
The doctoral is supervised by Hector Fellow A. Stephen K. Hashmi and aims at developing new ligands that are based on 1,3‑diketones to enlarge the chemical space of known ligands towards more electron rich ligands. First synthetic routes have to be found. Thereafter the obtained ligands have to be characterised by determining their steric and electronic influences as well as performing catalytic tests with them. Due to the shapes of the molecular orbitals of 1,3 diketones they are 4e-donors which is in contrast to common carben ligands that are only 2e-donors. This in combination with their, relative to the central donor atom remote heteroatoms, leads to the conclusion of them being extraordinary electron rich. By varying the residues, the steric demand can be widely tuned. Therefore it is to be anticipated that the new ligands can be used to make catalysts with increased activity and new selectivity.
Scheme: Commonly used ligand classes in catalysis. The doctoral aims to develop more electron rich 1,3 diketone based ligands for catalysis.
Jonas WunschUniversity of Heidelberg
A. Stephen K. HashmiChemistry
Hector Fellow since 2010