Support for young scientists from all over the world
Doctoral projects
@ Darius Rauch

Unveil­ing Circa­dian Function of Photore­cep­tors in Plants

Darius Rauch — Hector Fellow Peter Hegemann

 

My doctoral project focuses on identi­fy­ing light-sensi­tive proteins called photore­cep­tors in the model organ­ism Chlamy­domonas reinhardtii. I aim to answer how these recep­tors regulate the inner biolog­i­cal clock known as the circa­dian rhythm. My major focus is to deter­mine the proper­ties of an unknown red light-sensi­tive photore­cep­tor and how this recep­tor regulates the clock. These insights can be used to under­stand how plants, in general, process light information.

The differ­ent behav­iour of animals and humans during the day and night is regulated by an inner biolog­i­cal clock called the circa­dian rhythm. This rhythm is repre­sented within cells through the time-depen­dent abundance of proteins. Not only animals but also plants possess such a rhythm. Plant processes like photo­syn­the­sis are synchro­nized to the rotation of the planet Earth. In plants, this synchro­niza­tion is maintained through light signals being passed to the oscil­lat­ing proteins that make up the biolog­i­cal clock. This infor­ma­tion is trans­mit­ted through proteins called photoreceptors.

My doctoral project focuses on inves­ti­gat­ing how these photore­cep­tors function and how they inter­act with the circa­dian system. To this end, I am utiliz­ing the unicel­lu­lar algae Chlamy­domonas reinhardtii as a model organ­ism to inves­ti­gate how photore­cep­tor mutations affect the circa­dian rhythm. Follow­ing this approach, I have already identi­fied the plant-like cryptochrome pCRY as an essen­tial photore­cep­tor regulat­ing the circa­dian system. My research has also shown that a newly unchar­ac­ter­ized red light-sensi­tive photore­cep­tor regulates the clock. During my doctoral project, I will charac­ter­ize this novel red-light recep­tor and uncover how it is integrated into the circa­dian rhythm.

I will contex­tu­al­ize these findings within the broader topic of how plants regulate light, a subject that gains increas­ing relevance in the face of climate change and inten­si­fy­ing droughts

Zugang zu pi-erweiterten Carbazolen und deren Anwendung

The 24 hour circa­dian rhythm of the alga Clamy­domonas reinhardtii  (green, left) is maintained through differ­ent light signals during the day and night (indicated by moon and sun). These signals are trans­mit­ted by photore­cep­tors which have differ­ent light sensi­tiv­i­ties. Thes sensi­tiv­i­ties are indicated by the photore­cep­tor absorp­tion spectra in the background.

Darius Rauch

Humboldt-Univer­sität zu Berlin

Super­vised by

Prof. Dr.

Peter Hegemann

Biology, Chemistry & Medicine

Hector Fellow since 2015Disziplinen Peter Hegemann