Creat­ing the Future
Projects

High-through­put Virus Discov­ery in Next Gener­a­tion Sequenc­ing Data

Franziska Klingler – Hector Fellow Ralf Bartenschlager

Anelloviruses are a diverse group of ubiquitous viruses infecting humans and vertebrates. Their contribution to disease development remains elusive. We hypothesize that during lifelong, persistent infection disbalances in the viral community can drive onset and progression of disease, e.g. cancer. We aim at a thorough description of the viral spectrum present in healthy and diseased tissue by high-throughput screening of sequencing data and subsequent identification of viral variants correlated with pathogenesis.

© Franziska Klingler

Quantum infor­ma­tion process­ing with scalable semicon­duc­tor spin-qubit chips

Dominic Barthlott - Hector Fellow Wolfgang Wernsdorfer

Quantum computing has the potential to provide speedups for classical problems such as complex simulation, optimization and cryptography tasks, but requires scalable and reliable qubit technologies. Semiconductor spin qubits combine long coherence times with established industrial fabrication techniques. This project focusses on implementing high-fidelity two-qubit gates, which are then expanded to multi-qubit arrays and quantified by applying quantum information algorithms together with rigorous benchmarking.

© Koch, T., Godfrin, C., Adam, V. et al.

Beyond the Cortex: Subcor­ti­cal Connec­tiv­ity in Social Cognition

Lorenz Ahle - Hector RCD Awardee Sofie Valk

This project explores how subcortical structures such as the amygdala, thalamus, basal ganglia, cerebellum and hippocampus shape social cognition. Using high-resolution fMRI, diffusion MRI and computational modeling it examines how connections between subcortex and cortex support empathy, perspective taking and emotional regulation.

© Sofie Valk